Symptoms2026-03-13Carelogy編集部

Jaundice in Cats: Causes of Yellow Skin/Eyes, Diagnosis & Treatment

Why your cat's skin, eyes, or gums turned yellow: liver disease, hemolytic anemia, bile duct obstruction — diagnosis and treatment options.

Key Takeaway: Jaundice in Cats Is an Emergency Sign — See a Vet Within 48 Hours

If your cat's skin, whites of eyes, gums, or inner ears appear yellow, this is jaundice (icterus). It's caused by bilirubin accumulation and signals serious disease. How to spot jaundice: - Inner ears (thin fur makes yellow visible) - Whites of eyes (scleral icterus) - Gums (yellow tint instead of pink) - Paw pads (easier on white/light-colored cats) - Belly skin (areas with thin fur) Three categories of jaundice: | Type | Cause | Characteristics | |------|-------|----------------| | Pre-hepatic (hemolytic) | Excessive red blood cell destruction | Anemia + jaundice | | Hepatic | Liver damage | Lethargy + appetite loss + jaundice | | Post-hepatic (obstructive) | Bile duct blockage | Abdominal distension + jaundice | Urgency: Cats with jaundice need a vet visit within 48 hours. If suddenly lethargic, go today.

Specific Diseases That Cause Jaundice

Liver diseases (most common): - [Hepatic lipidosis (fatty liver)](/en/columns/cat-liver-disease): Most common cause of jaundice in cats. Can develop after just 2-3 days of not eating. Watch overweight cats that stop eating - Cholangitis/cholangiohepatitis: Bacterial infection of bile ducts. Fever + jaundice + appetite loss - [FIP (Feline Infectious Peritonitis)](/en/columns/cat-fip): Dry form affecting the liver causes jaundice - Liver tumors: Lymphoma, etc. More common in senior cats Blood diseases (hemolytic): - Immune-mediated hemolytic anemia (IMHA): Autoimmune destruction of red blood cells. Acute and dangerous - [FeLV (Feline Leukemia Virus)](/en/columns/cat-felv-fiv) infection: Causes anemia - Onion/chive toxicity: From eating toxic foods - Hemoplasma infection: Tick-borne blood parasites Bile duct obstruction: - Gallstones: Rare but possible in cats - [Pancreatitis](/en/columns/cat-pancreatitis): Pancreatic swelling compresses bile duct (triaditis) - Tumors: Bile duct or duodenal tumors blocking bile flow
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Veterinary Testing & Diagnosis

Multiple tests are needed to identify the cause of jaundice. | Test | Purpose | Cost | |------|---------|------| | Blood work | Bilirubin levels, liver enzymes, anemia degree | ¥5,000-15,000 | | Blood smear | Red blood cell morphology, parasites | ¥2,000-5,000 | | Abdominal ultrasound | Liver, gallbladder, bile duct status | ¥3,000-10,000 | | X-ray | Liver size, masses | ¥3,000-8,000 | | FeLV/FIV test | Viral infection screening | ¥3,000-8,000 | | Urinalysis | Bilirubinuria confirmation | ¥2,000-5,000 | | Liver cytology/biopsy | Definitive diagnosis (ultrasound-guided) | ¥10,000-30,000 | Reading results: - Total bilirubin > 2.0 mg/dL: Visible jaundice - ALT/AST elevated: Liver cell damage - ALP/GGT elevated: Biliary system issue (suggests obstructive jaundice) - PCV (packed cell volume) decreased: Suggests hemolytic jaundice Critical results: - PCV below 15% (severe anemia — may need transfusion) - Bilirubin above 10 mg/dL (severe jaundice) - Low platelets + anemia (possible DIC — disseminated intravascular coagulation)

Treatment by Cause & Costs

Hepatic lipidosis treatment: - Force-feeding via nasal/esophageal tube (most critical treatment) - Liver support supplements (SAMe, silymarin) - Hospitalization: 5-14 days, cost ¥100,000-300,000 - 60-80% recovery rate with early treatment Cholangitis treatment: - Antibiotics (amoxicillin-clavulanate, etc.) for 4-6 weeks - Choleretic drugs (ursodeoxycholic acid) - Cost: ¥10,000-30,000/month IMHA treatment: - Immunosuppressants (prednisolone + cyclosporine) - Blood transfusion in severe cases - Hospitalization: ¥50,000-150,000 - Ongoing medication: ¥5,000-15,000/month Bile duct obstruction treatment: - Surgery (cholecystectomy, stent placement, etc.) - Surgery cost: ¥100,000-400,000 - Pancreatitis-related cases may improve with medical management [Pet insurance](/en/columns/cat-insurance-guide) matters: Jaundice treatment tends to be expensive — insurance is recommended.

Prevention & Early Detection Tips

Preventing jaundice = preventing underlying diseases: Preventing hepatic lipidosis (most important): - Never let your cat go without food for 2+ days. This is the biggest prevention measure - If an overweight cat stops eating, see a vet immediately - Watch for appetite drops from stress or changes (moving, new cat, etc.) - Monitor appetite daily with CatsMe's food tracking Preventing hemolysis: - Never feed toxic foods (especially onions, chives, garlic) - FeLV vaccination - Flea/tick prevention (prevents Hemoplasma infection) Early detection tips: - Weekly check of inner ear and gum color (normal is pink) - Stay alert to appetite changes - Lethargy + not eating → may be early jaundice signs - Annual (biannual for 7+) blood work to check liver enzymes Detect changes early with CatsMe: AI analyzes daily facial expressions, catching signs of lethargy and appetite loss. Late discovery of jaundice can be fatal — daily monitoring saves lives.
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